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Smokeless tobacco irritates the gums and as a result, the gums begin to separate from the teeth

According to a recently published market study by Facts and Factors Research, it was forecasted that The Global E-Cigarette and Vape Market was valued at $15.04 billion in 2020 and is forecasted to reach $33.92 billion by 2027, expanding at a CAGR of 13.37%

The nicotine patch is the most commonly used [6] form of NRT but is less effective in heavy smokers ( 20 cigarettes/day) presumably due to inadequate replacement of nicotine to treat withdrawal, suggesting that higher doses may be more effective [14, 15]