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Where to Go from Here Where to Go from Here The central problem of premarket review is not, as Dobbins contends, that FDA has made it too difficult to get e-cigarettes to market, but that the agency has allowed so many manufacturers, particularly of flavored products, to market their products while avoiding the obligation to demonstrate, prior to reaching the market, that their e-cigarettes are appropriate for the protection of the public health. This regulatory holiday has caused, and continues to cause, great harm to public health

There are over 4,000 toxic chemicals in most every cigarette

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These overlarge chains are mom-and-pop killers, said Cohen, the Columbia professor