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Several decisions were close, and the committee heard substantial disagreement about chemical characterization, peptide-related impurities, immunogenicity, carcinogenicity signals or uncertainty, the limited quantity and quality of human evidence, and whether existing FDA-approved therapies already address the proposed uses

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The published experiments did not directly remove VEGFR2 and then show that the full Src-related response remained unchanged

DoW SBIR/STTR BAAs and CSOs are published at two sites