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Efficacy and safety of once-monthly efpeglenatide in patients with type 2 diabetes: results of a phase 2 placebo-controlled, 16-week randomized dose-finding study

This can likely be attributed to the action GLP-1 RAs exert on the central nervous system and brain function.15 While effective at reducing caloric intake, we consider it a side effect, as our testing team generally regarded it as an unpleasant experience

Tirzepatide has a half-life of five days, meaning the medication remains in your system for weeks

Adding mild acidic flavors such as lemon juice to meals can help mask unpleasant tastes, though be cautious with acidic foods if you experience reflux symptoms