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This finding was corroborated by in vivo studies using a CRC mouse model in which BALB/c mice treated with Exe-9 exhibited significantly attenuated tumor growth and increased intratumoral infiltration of CD8+ T cells, which were absent in nude mice lacking functional T cells

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Contact your GP or prescribing clinician if you experience complete absence of periods (amenorrhoea) for three consecutive months or longer, particularly if you are under 45 years of age and this represents a change from your usual pattern

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