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doi: 10.3390/ijms24043074 52 DanemanR

TNF--induced NF-B pathway activation plays a part in psoriasis, and TNF- monoclonal antibodies have been employed in clinical settings for psoriasis treatment [27]

These findings collectively define a novel GPR68-PI3K/Akt-Nrf2 axis as a central regulatory node in ferroptosis pathophysiology and provide preclinical validation for repurposing Lorazepam to mitigate SCIRI