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Method Literature search strategy Google Scholar and PubMed were searched on various dates between December 2016 and March 2017, ending on 15th March 2017 using the following terms, and variants thereof, and all articles discovered were considered for inclusion: (paracetamol OR acetaminophen hepatotoxicity) AND genetic differences/polymorphisms OR children/neonates/young people/paediatric OR older people/elderly/geriatric OR nutritional state/malnutrition OR body weight/low body weight OR alcohol/alcohol-dependence OR drug interactions/potentiation OR liver disease/chronic liver disease/liver failure
doi: 10.1016/j.cub.2013.04.024 28 MumbySMKleussCGilmanAG
Although these symptoms might be categorized as benign they can result in poor sleep patterns and their impact on quality of life feels anything but benign
Iron overload can drive oxidative stress, which in turn can induce senescence and fibrosis [27]
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