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Not recommended for: Patients with a history of pancreatitis Those with medullary thyroid carcinoma or MEN2 Pregnant or breastfeeding individuals People with severe gastrointestinal disorders (e.g., gastroparesis) For individuals who are not suitable for these options, alternative prescription weight loss options may be explored , such as bupropion-naltrexone (Contrave) or phentermine-topiramate (Qsymia), depending on the clinical picture

The nonessential amino acid cysteine is required to prevent ferroptosis in acute myeloid leukemia

Carefully adjust dose for patients on anticoagulant therapy under cardiological/hematological management

But they havent been around for very long, so we dont have a wealth of history to draw on