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The role of glutathione and glutathione S-transferases in the metabolism of chemical carcinogens and other electrophilic agents

This story is by Madeleine Kates and was originally published in the spring 2025 issue of University of Pennsylvania School of Nursing Magazine.

On the other hand, in cholestatic individuals in whom the NGS panels have not found pathogenic mutations, a comprehensive study like WES, performed over the full exome, can find potential gene candidates for a cholestasis association, as was the case with the most recently discovered PFIC, PFIC 13 [37, 90]

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