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As for how these meds work, they mimic GLP-1, a naturally occurring hormone made in the small intestine that lowers the amount of glucose (sugar) in your blood and slows stomach emptying, helping send the signal to your brain that keeps you feeling full and satiated longer after eating

Mechanisms of action and therapeutic application of glucagon-like peptide-1. Cell Metabolism.

Cotargeting proteins involved in glutamine metabolism and the stress response under conditions of glutamine depletion would therefore be a promising therapeutic strategy for overcoming adaptive/resistance mechanisms in cancer cells

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