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172 Rodent 173 and human studies 174 reveal that leptin also modulates glucose and lipid metabolism through a brainvagusliver axis and hypothalamicpituitaryadrenal signaling, contributing to adverse communication among adipose tissue, the hypothalamus, the liver and the pancreas, exacerbating T2D

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Michael DeShields, MD, the clinical adviser of the Discovery Institute in New Jersey, says access to Wegovy has improved over time, but insurance companies like Aetna still cover it inconsistently