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Studies in mice show that sucrose and umami stimuli can promote GLP-1 secretion from taste bud-like cells, reinforcing the link between nutrient detection and enteroendocrine signaling ( Umami taste receptors (TAS1R1/TAS1R3 heterodimers) also respond to amino acids such as glutamate and aspartate

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[1] [2] These effects may lead to decreased food intake and potentially impact overall nutritional status over time