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Therefore, regulation of peripheral Th1, Th17, and Treg cell differentiation by intervening glutaminolysis in nave CD4 + T cells shows great potential to be exploited in immune-excessive diseases
Optimal ROS levels are essential for cellular functions such as cell proliferation, differentiation, and apoptosis 15,16,17
1 Institute for Health Services Research and Health Economics, German Diabetes Center, Duesseldorf, Germany, 2 German Center for Diabetes Research, Mnchen-Neuherberg, Germany, 3 Institute for Health Services Research and Health Economics, Centre for Health and Society, Medical Faculty and University Hospital Dsseldorf, Duesseldorf, Germany, 4 mediStatistica, Neuenrade, Germany, 5 winDiab gGmbH, Neuss, Germany, 6 Institute for Health Services Research and Health Economics, Centre for Health and Society, Medical Faculty and University Hospital Dsseldorf, Dsseldorf, Germany
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