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doi: 10.3389/fphar.2025.1719384 Received 06 October 2025 Revised 01 November 2025 Accepted 03 November 2025 Published 26 November 2025 Volume 16 - 2025 Edited by Gvozden Rosic, University of Kragujevac, Serbia Reviewed by Kandasamy Neelamegam, Tulane University, United States Ciniraj Raveendran, Government Medical College, India Updates Copyright 2025 Yan, Song, Zhang, Hu, Wang, Guo, Wang, Ma and Liu

Pre-infusion CAR T cells of long-term responders (LTR) have increased oxidative phosphorylation, fatty acid oxidation, and pentose phosphate pathway activities, higher mitochondrial mass, tighter cristae, and lower mTOR expression compared to products of short-term responders

Complex carbohydrates, including oats, brown rice, sweet potatoes, legumes, and whole grain bread, provide sustained glucose release that stabilizes blood sugar and reduces the hypoglycemic states that can trigger or intensify alcohol cravings

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