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Inhibition of cannabinoid receptor type 1 sensitizes triple-negative breast cancer cells to ferroptosis via regulating fatty acid metabolism

FOXO4-DRI shows potential as a treatment targeting the senescence and apoptosis resistance, and holds promise as an approach to prevent the aggressiveness and relapse of keloids

The recommendations of the GIRO guide (Spanish Guide for the Comprehensive and Multidisciplinary Management of Obesity in Adults), conducted with the participation of 38 scientific societies and 12 patient associations in Spain, state that drug treatment for obesity should be considered in individuals with a BMI 27 kg/m 2 with at least one complication related to adiposity present, including T2DM, high blood pressure, OSA, CVD, heart failure (HF) and osteoarthritis, among other health problems or in individuals with a BMI 30 kg/m 2 regardless of the presence of adiposity-related complications [31]

Other publications discussed: user-friendly intuitive eCOA design, flexible data collection and monitoring methods, patient-centered protocol design, and comprehensive participant and site training