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We began with the steady state for S = 1.8, but changed the value of S to 1.3 at t = 0, where the steady state of GSH is 6,842 M

Phase 1b (9-24 months): Steady growth with a typical rate of weight gain

In a model mimicking severe nephritis, which is essentially 100 percent lethal to the kidneys in humans and deadly to the mouse model, with treatment there was instead an 80 percent survival of the mice

Genetic factors involved in gut microbiota composition and bile metabolism Genetic factors significantly influence immune and inflammatory response, altering liver function, gut microbiota composition, and bile metabolism [44]