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Among these, 7 key targets (HSP90AA1, CASP3, KRAS, ERBB2, BCL2L1, GRB2, and SHC1) were up-regulated in BRCA, and the remaining 5 key targets were down-regulated

[PubMed] [Google Scholar] 12.Zhao X., Yeh J.Z., Narahashi T

The subsequent literature never converged on DSIP being a sleep-inducing agent in any conventional sense, and its own principal investigators repeatedly noted effects that had nothing to do with sleep: stress tolerance, pain, withdrawal syndromes, chronobiological regulation