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(Dependent on patient's needs) Dose: 250 g (also known as micrograms(mcg))in cats and 250 2000 g (also known as micrograms (mcg))in dogs, depending on the size of the patient: For parenteral cobalamin supplementation: Protocol: weekly injections for 6 weeks, then one dose a month later, and retesting one month after the last dose( dependent on patient's needs) For either oral or parenteral supplementation, if the underlying disease process has resolved and cobalamin body stores have been replenished, serum cobalamin concentration should be supranormal at the time of reevaluation

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Within body tissues, the specific B12 binding proteins transcobalamin I and II facilitate the absorption of cyanocobalamin into the cells.1017 Cyanocobalamin is a cofactor for the synthesis of two major enzymes in the body namely methionine synthase and L-methymalonyl-CoA mutase