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Within the technique of immunohistochemistry, special mention must be made of preferentially expressed antigen in melanoma antibody (PRAME), whose expression in the nucleus should give cause for concern in the case of a histologically atypical melanocytic lesion.74,75 Staining with PRAME should not be evaluated in absolute terms (positive/negative), but rather in relative terms (intensity and percentage of staining)

As discussed in the previous paragraph, endometrial organoids, both mouse and human-derived, have been successfully employed as grafts to treat post-traumatic endometrial regeneration disorders in mouse models [80, 81]

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