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Future Directions Due to the detrimental effects of ROS exerted through the oxidation of essential molecules such as enzymes and cytoskeletal proteins [144,145], a therapy based on the elimination of excess ROS is potentially a tractable approach

doi: 10.3390/ijms21176206 135 ShouYYangLYangYXuJ

In this setting, if gluconeogenic flux and/or glycogenolysis are also compromised as a result of inadequate substrates for gluconeogenesis (e.g., reduced AAs), subnormal glycogen storage (low caloric intake), or reduced counterregulatory hormones, hypoglycemia at late postprandial time points could ensue