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(2021) Epigenet Insights, 14:25168657211006159

00:08 Portrait of attractive blonde woman smoking electronic cigarette at home interior 00:21 A girl reads a book in the park while smoking and starts yawning 00:07 Beautiful young redhair woman smoking 00:07 Portrait of a attractive blonde woman with electric cigarette 00:17 Beautiful young woman smoking a cigarette in the dark 00:12 Young beautiful woman with curly hair smoking cigarettes near the open window 00:09 Beautiful young redhair woman smoking 00:09 LYNBROOK, NEW YORK 1974: Man holding newborn baby wrapped in blanket near smoking woman 00:13 Close up side view of woman vaping and exhaling smoke

The long-term cigarette smoking also causes structural and compositional changes in the skin associated with an accelerated aging phenotype, deep wrinkles, loss of elasticity, pigmented spots, sallow coloration, and impaired wound healing 2

lavaan: an R package for structural equation modeling