Mitochondrial function was severely compromised on multiple levels, including abnormalities in mitochondrial biogenesis (PGC1), nutrient sensors regulating fatty-acid entry into mitochondria (pAMPK/AMPK, SirT3, CPT1b), mitochondrial -oxidation of fatty-acids (HADHA, PPAR), electron transport chain complexes (I, II, III, V), ATP synthesis (ATP5A), and mitophagy (PINK1)
These headaches are often referred to as glutathione headaches and can be quite debilitating, causing nausea, dizziness, and sensitivity to light
Its likely that it will have the opposite effect, as it improves insulin resistance and reduces blood glucose production in the liver
Immune function: As a master antioxidant, glutathione supports immune cell production and function, particularly in lymphocytes