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Tesamorelin is FDA-approved to reduce abdominal fat in HIV patients with lipodystrophy, but physicians now apply it more broadly to help aging adults reduce visceral fat and support metabolic health

It can cause some side effects including stomach upset, nausea, vomiting, dry mouth, headache, and restlessness

Up until 2023, pediatricians were advised to apply a watchful waiting approach with patients diagnosed with obesity, and to recommend lifestyle treatments aimed at healthier eating and exercise habits

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