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In general, the longer-acting GLP-1 agonists which are injected weekly, such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro), are associated with greater weight loss than the shorter-acting GLP-1 agonists such as liraglutide (Saxenda)

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Liver damage may occur after taking as few as four or five extra-strength pills over the course of the day, one NIH publication on alcohol and metabolism says