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These include: Nausea (affecting 2040% of patients initially) Vomiting and diarrhoea Constipation Abdominal discomfort or bloating Reduced appetite These symptoms are usually mild to moderate and tend to diminish over several weeks as the body adjusts to the medication

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It converts moreharmful hydroxyl ions into hydrogen peroxide Vitamin C in cytoplasm Ferritin and Ceruloplasmin present in cytoplasm Levels of active forms of iron and copper are minimized by binding of ions to storage and transport proteins like transferrin, ferritin, ceruloplasmin there by minimizing the formation of hydroxyl ion Vitamins E, A and Carotene in the plasma membrane and cell membrane of organelles

According to XANES, all of the copper ions were Cu(II)